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Laboratory evaluation of depth of focus for presbyopia-correcting IOLs

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Session Details

Session Title: Presented Poster Session 05: Cataract Surgery Outcomes / IOL Technology

Session Date/Time: Saturday 13/09/2014 | 15:00-17:00

Paper Time: 16:00

Venue: Pod 2 (Poster Village)

First Author: : H.Weeber THE NETHERLANDS

Co Author(s): :    D. Chang   P. Piers           

Abstract Details


Today, more intraocular lens (IOL) designs are available that target an improved range of vision. In this study, we investigate the depth of focus of IOL designs using innovative methodologies.


AMO Groningen, Netherlands


The depth of focus (DOF) was assessed for monofocal, multifocal, and trifocal, and new designs. Through-focus image quality was evaluated with optical bench testing in white light. The optical bench consisted of a model eye that incorporates a glass cornea, a wet cell, and a camera for imaging. The model eye mimics the average spherical aberration and chromatic aberration of the eye. The focal position was varied in steps of 0.125 diopters. Images of the US Air Force target were recorded, and the modulation transfer function and pupil size dependency were measured.


The optical bench tests show large differences compared to clinical experience, especially at intermediate distances. The difference between the bench tests and clinical experience is explained by the computer simulations. Area-under-the-MTF and images of the US Air Force target provide best indications of measured range of functional vision. Increasing the pupil from 3.0mm to 5.0mm reduced the MTF at near by 0% to 65%, depending on lens design. For the trifocal IOLs, the intermediate MTF decreased about 40% when the pupil is increased from 3.0mm to 5.0mm. Pupil independent behavior was found only in full-diffractive designs.


Different evaluation techniques were used to assess DOF. Each of these methods has its own characteristics. The results show that the performance of almost all IOL designs is dependent on pupil size. Pupil independent behavior was found only in full-diffractive designs.

Financial Interest:

One or more of the authors... is employed by a forNONEprofit company with an interest in the subject of the presentation, One or more of the authors... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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