A prospective, randomized, eye-to-eye comparison of wavefront-guided PRK versus wavefront-optimized PRK on a 400 Hz excimer laser: preliminary results

Session Details

Session Title: Presented Poster Session 07: Keratorefractive Surgery Outcomes - Myopia 2

Session Date/Time: Sunday 14/09/2014 | 09:30-11:00

Paper Time: 10:00

Venue: Pod 1 (Poster Village)

First Author: : E.Manche USA

Co Author(s): :                  

Abstract Details

Purpose:

To prospectively compare outcomes between wavefront-guided PRK and wavefront-optimized PRK using the Alcon Wavelight Eye-Q 400 Hz excimer laser in the treatment of myopia. Outcome measures include high contrast snellen acuity, low contrast snellen acuity (25% and 5%), safety, efficacy, predictability and higher order aberration analysis.

Setting:

Academic based refractive surgical service

Methods:

Thirty-four eyes of 17 consecutive patients were treated with wavefront-guided and wavefront-optimized PRK. Both eyes were treated with the Alcon Allegretto Wave Eye-Q 400 Hz excimer laser system. Eyes were randomized according to ocular dominance. The mean pre-operative spherical equivalent refraction was -3.08 +/- 1.43 and -3.23 +/-1.42 in the wavefront-guided group and wavefront-optimized group respectively. The mean cylinder was +0.47 +/-1.04 and +0.58 +/-0.98 in the wavefront-guided group and wavefront-optimized group respectively. There were no statistically significant differences in pre-operative higher order aberrations between the two groups.

Results:

At post op month three, 91% of eyes in the wavefront-guided group and 92% of eyes in the wavefront-optimized group were within 0.50 diopters of the intended correction. At the 3-month post-op visit the mean spherical equivalent refraction was +0.23+/- 0.29 in the wavefront-guided group and +0.31 +/- 0.33 in the wavefront-optimized group. At 3-months, the mean cylinder was reduced to +0.27 +/- 0.27 in the wavefront-guided group and +0.32 +/- 0.28 in the wavefront-optimized group. At 3-months the mean total higher order RMS value was increased from 0.35 microns in both groups to 0.38 microns and 0.39 microns in the wavefront-guided group and wavefront-optimized group, respectively.

Conclusions:

Wavefront-guided and wavefront-optimized PRK had similar predictability, efficacy and safety in the short term. Longer-term follow-up is ongoing.

Financial Interest:

NONE