Femtosecond-assisted myopic LASIK: one year comparison of LASIK combined with prophylactic high-fluence cross-linking to stand-alone LASIK

Session Details

Session Title: Presented Poster Session 04: Femto Laser 1

Session Date/Time: Saturday 13/09/2014 | 15:00-17:00

Paper Time: 16:45

Venue: Pod 1 (Poster Village)

First Author: : A.Kanellopoulos GREECE

Co Author(s): :    G. Asimellis              

Abstract Details

Purpose:

To evaluate safety, efficacy, and refractive and keratometric stability of myopic femtosecond-LASIK with concurrent prophylactic high-fluence cross-linking (CXL) in comparison to standard femtosecond LASIK.

Setting:

Laservision.gr Eye Institute, Athens, Greece

Methods:

140 eyes of consecutive patients with myopic LASIK were recruited. Group-A represents 65 eyes treated additionally with concurrent prophylactic high fluence CXL (LASIK-Xtra); group-B represents 75 eyes subjected to stand-alone procedure. The following parameters were evaluated pre-operatively and one-year post-operatively: manifest refractive spherical error (MRSE), refractive astigmatism, spectacle-corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA), and corneal keratometry via Scheimpflug imaging and autorefraction keratometry.

Results:

Group-A (LASIK-Xtra) had an average postoperative average manifest refractive spherical equivalent -0.23, -0.19 and -0.25 D for the 3-, 6-, and 12-month period, compared to -6.75±1.75 D preoperatively. Flat keratometry was 37.69, 37.66, and 37.67 D for the same period, compared to 43.92 preoperatively, and steep keratometry was 38.35, 38.36, and 38.37 D for the 3-, 6-, and 12-month period, compared to 45.15 D preoperatively. Predictability had a correlation coefficient of 0.975. Group-B (stand-alone LASIK) had an average postoperative average manifest refractive spherical equivalent -0.23, -0.20 and -0.27 D for the 3-, 6-, and 12-month period, compared to -5.33±2.34 D preoperatively. Flat keratometry was 37.65, 37.89, and 38.02 D for the same period, compared to 43.15 preoperatively, and steep keratometry was 38.32, 38.57, and 38.66 D for the 3-, 6-, and 12-month period, compared to 44.03 D preoperatively. Predictability had a correlation coefficient of 0.968.

Conclusions:

Application of prophylactic cross-linking concurrently with high-myopic LASIK operation appears to contribute to improved refractive and Keratometric stability in comparison to the stand-alone LASIK. The procedure is safe and opens up a new potential for LASIK application in myopic corrections.

Financial Interest:

One or more of the authors... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented