Assessment of anterior chamber parameters in patients with angle-supported phakic intraocular lens using optical coherence tomography

Session Details

Session Title: Interactive Free Paper Session: Anterior chamber phakic IOLS

Session Date/Time: Tuesday 16/09/2014 | 16:30-18:00

Paper Time: 17:30

Venue: Auditorium

First Author: : D.Pokrovskiy RUSSIA

Co Author(s): :    A. Shpak   B. Malyugin           

Abstract Details

Purpose:

To assess anatomical parameters of the anterior chamber of the eye in patients with angle-supported phakic intraocular lens (PIOL) using anterior segment optical coherence tomography (AS-OCT).

Setting:

S. Fyodorov Eye Microsurgery Complex–Federal State Institution, Moscow, Russian Federation.

Methods:

We studied seventeen highly myopic patients (31 eyes, mean age 25.8±4.6 years) corrected with angle-supported PIOL Cachet (Alcon). Mean spherical equivalent was -12.38±3.64D. AS-OCT (Visante OCT, Carl Zeiss Meditec AG) was performed pre- and postoperatively in all eyes. Preoperatively we measured horizontal and vertical anterior chamber diameters (Angle-to-Angle, ATA) and anterior chamber depth (from corneal epithelium and endothelium). Also in 3 to 12 months postoperatively we assessed the following parameters: “PIOL – corneal endothelium” (central), “PIOL – natural lens” (central) and “PIOL edge – corneal endothelium” (temporal and nasal).

Results:

Mean preoperative horizontal and vertical anterior chamber diameters were 12.07±0.38 mm and 12.46±0.44 mm respectively (P<0.001). Mean anterior chamber depth values from corneal epithelium and corneal endothelium were 3.88±0.31 mm и 3.36±0.33 mm respectively. Mean distance “PIOL – corneal endothelium” was 2.19±0.19 mm, “PIOL – natural lens” – 0.92±0.15 mm, temporal “PIOL edge – corneal endothelium” – 1.55±0.18 mm and nasal “PIOL edge – corneal endothelium” – 1.53±0.18 mm. In 10 out of 31 eyes (6 patients) we found that both nasal and temporal “PIOL edge – corneal endothelium” parameters were “dangerous” – less than 1.5 mm. Using the stepwise discriminant analysis we created classification formula (reliable with P<0,005) and simplified algorithm to predict the risk of “dangerous” Cachet position in the anterior chamber of the eye. On our clinical material sensitivity and specificity of this formula were 100% and 95% respectively.

Conclusions:

Current study showed that existing patient selection criteria for Cachet PIOL do not provide its safe position in some cases. New prediction formula and algorithm allow identifying patients at risk to enhance the efficiency and safety of this high myopia correction method.

Financial Interest:

NONE