Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy

Session Details

Session Title: Surface Ablations for Correction of Ammetropias

Session Date/Time: Tuesday 16/09/2014 | 08:00-10:30

Paper Time: 08:00

Venue: Auditorium

First Author: : A.Eslampoor IRAN

Co Author(s): :    M. Abrishami              

Abstract Details

Purpose:

The purpose of this study was to evaluate the efficacy of extended-release diclofenac for the management of pain after PRK surgery.

Setting:

Cornea research center,Khatam-al anbia Eye Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

Methods:

Prospective clinical trial study. Patients in the case group were given extended-release diclofenac pre- and postoperatively, and patients in the control group were given acetaminophen and ibuprofen preand postoperatively. Patients were examined 2 days after PRK surgery. Pain, photophobia, and functional deficit scores were evaluated subjectively for each patient. An ophthalmologist evaluated lid swelling, conjunctival injection, and epithelial healing.

Results:

Among the 62 patients enrolled in the study, 33 patients were given extended-release diclofenac (case group) and 29 patients were given acetaminophen and ibuprofen (control group). The pain score was reduced in the case group compared to the control group (4.32 – 2.72 vs. 6.52 – 1.99, respectively; P < 0.001). Photophobia, functional deficit scores, lid swelling, and conjunctival injection were significantly reduced in the case group compared to the control group.

Conclusions:

The results indicate that oral diclofenac (preoperatively) is more effective than other routine analgesics in the management of pain in PRK surgery.

Financial Interest:

NONE