Is optical coherence tomography an effective device for evaluation of tear film meniscus in patients with acne rosacea?

Session Details

Session Title: Special Cases

Session Date/Time: Sunday 14/09/2014 | 14:30-16:00

Paper Time: 15:12

Venue: Boulevard B

First Author: : F.Corak Eroglu TURKEY

Co Author(s): :    A. Karalezli   R. Dursun           

Abstract Details

Purpose:

To investigate the tear meniscus using Fourier-domain optical coherence tomography (FD-OCT) in patients with acne rosacea and to determine the relationship between tear film break-up tests, Schirmer test and FD-OCT values and to compare them with that of healthy controls.

Setting:

Baskent University School of Medicine, Department of Ophthalmology,Konya, Turkey

Methods:

One hundred four patients with acne rosacea and 104 body mass index-age -sex matched healthy subjects were enrolled in this prospective case-control study. Tear meniscus height (TMH), depth (TMD) and tear meniscus cross-sectional area (TMA) were measured using FD-OCT (RTVue-100); tear film break-up time (TBUT), Schirmer test and dry eye questionnaire (OSDI) were evaluated. Correlation was assessed using Spearman’s correlation coefficient.

Results:

Mean TMH, TMD, TMA,TBUT and Schirmer test values of acne rosacea patients were significantly lower than and OSDI score significantly higher than those of controls. Tear mensicus values were significantly correlated with OSDI scores, TBUT and Schirmer test results. The intraobserver ICC for tear paramaters ranged from 0.90 to 0.96 and interobserver ICC ranged from 0.92 to 0.94, which revealed high reprodubility for all measurements parameters both acne rosacea and control subjects. Accuracy of dry eye diagnosis by FD-OCT was 60.4% for TMH, %58.7 for TMD, %64.8 for TMA.

Conclusions:

Tear meniscus measurement with FD- OCT could provide acceptable specificity and sensitivity in diagnosis of dry eye in acne rosacea patients.

Financial Interest:

NONE