Official ESCRS | European Society of Cataract & Refractive Surgeons
London 2014 Registration Visa Letters Programme Satellite Meetings Glaucoma Day 2014 Exhibition Hotel Booking Virtual Exhibition Star Alliance
london escrs

Course handouts are now available
Click here


Come to London

video-icon

WATCH to find out why


Site updates:

Programme Updates. Programme Overview and - Video Symposium on Challenging Cases now available.


Posters

Search Abstracts by author or title
(results will display both Free Papers & Poster)

Refractive outcomes of topography-guided photorefractive keratectomy with simultaneous cross-linking for keratoconus

Poster Details

First Author: D.Lin CANADA

Co Author(s):    S. Holland   G. Moloney   J. Tan        

Abstract Details



Purpose:

Evaluate refractive outcomes, efficacy and safety of simultaneous topography-guided photorefractive keratectomy (TG-PRK) with collagen cross-linking (CXL) for keratoconus (KC) using a neutralization technique and determine degree of hyperopic effect of CXL induced keratometric flattening after first year

Setting:

Private Laser Refractive Clinic

Methods:

Epithelial removal by trans-epithelial laser, riboflavin 0.1% until aqueous staining, UV irradiation 370nm 8-15 minutes, 3mW/cm2 - 5.4 J/m2 , hypotonic riboflavin if less than 400um, bandage contact lens, standard post PRK management Degree of refractive correction based on residual stromal depth of 300 microns with target correction of -1.25 diopters (D). Symptom score (10 point) , uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), keratometry (K), efficacy, and safety were at 12 months.

Results:

215 eyes completed 12 months follow-up. 102 eyes (47%) had UCVA of 20/40 or better. 36 eyes (17%) had UCVA of 20/25 or better. 118 eyes (55%) had BSCVA improved, 47 eyes (22%) gained 2 lines or more, 13 eyes (6%) lost 2 lines or more. Average symptom score improved from 6.7 to 4.2 Mean reduction of astigmatism was 1.52 diopters (D). Complications included 7 with delay in epithelial healing, 4 with subsequent haze, 2 sufficient to reduce BCVA more than 2 lines, with one undergoing keratoplasty. One developed herpetic keratitis recovering pre-operative BCVA after PTK.

Conclusions:

Early satisfactory refractive outcomes were obtained with simultaneous topographically-guided PRK with CXL. Progressive hyperopia probably related to cross linking, sufficient to be visually significant, occurred in 4 eyes. At one year follow-up, close to half of the eyes achieved UCVA of 20/40 or better and a half improved BSCVA FINANCIAL INTEREST: NONE

Back to Poster listing