Posters

Presbyopia reversal: accommodation research using femtosecond lasers

Poster Details

First Author: S.Shah UK

Co Author(s):    H. Uy   R. Gil-Cazorla   S. Naroo   A. Pillai     

Abstract Details

Purpose:

Restoration of flexibility to the crystalline lens is needed for successful reversal of presbyopia in order to permit sliding of the fibers needed for changes in lens shape during accommodation. The purpose of this study was to determine the effect of in vivo femtosecond lenticular treatments on accommodative amplitude.

Setting:

Private ambulatory care centre

Methods:

Prospective evaluation of 80 patients undergoing cataract surgery and 20 undergoing clear lens extraction who were treated with a range of treatment algorithms. All were <55 years of age with ≤Grade 2 cataract and agreed to a minimum of 1 month follow-up before lens removal. Patients' visual axes were spared in order to limit subjective symptoms. Follow-up visits were at Weeks 1 and 2 and Month 1.

Results:

After one week, 33.3% showed an improvement in objective accommodation (measured with Grand Seiko autorefractor) and 53% of subjects showed an improvement in subjective accommodation (push down method). BDCNVA improved in 37.3% of patients at Week 1, improving to 40.8% at Month 1. In patients that showed an increase over baseline, maximum improvement in at Month 1 was 1.5 D and 2.3 D for objective accommodation and subjective accommodation, respectively. Mean improvement in BCDVA in patients with an increase from baseline was 31 letters at Month 1.

Conclusions:

In-the-lens treatment can improve objective and subjective accommodation and DCNVA in many patients. Remaining challenges include assessing objective accommodation with comprehensive systems such as aberrometry, the need for improvement in algorithms to increase the percentage of patients benefitting from treatment, and enhancing the improvement in accommodation. FINANCIAL INTEREST: One of more of the authors... is employed by a forNONEprofit company with an interest in the subject of the presentation, One of more of the authors... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One of more of the authors... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One of more of the authors... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented