Posters

The use of microperimetry in the assessment of central retinal sensitivity in patients with pituitary adenomas

Poster Details

First Author: M.Sarnat-Kucharczyk POLAND

Co Author(s):    E. Mrukwa-Kominek              

Abstract Details

Purpose:

To evaluate if microperimetry can be an alternative to different perimetric tests in patients with pituitary adenoma. To assess the relationship between the central retinal sensitivity and contrast sensitivity. To evaluate the usefulness of microperimetry and contrast sensitivity testing as supporting methods of diagnosing expansion of pituitary adenomas.

Setting:

Department of Ophthalmology, University Center of Ophthalmology and Oncology, Silesian University of Medicine, Katowice, Poland

Methods:

The analyzed group consisted of 40 patients diagnosed with pituitary adenoma based on magnetic resonance imaging (MRI). Patients were divided into two groups based on the outcome of MRI of the pituitary gland: - Group 1 - microadenoma of the pituitary gland - tumors with diameter < 1 cm - Group 2 - macroadenoma of the pituitary gland ¬- tumors with diameter ≥ 1 cm Patients were subjected to the following tests: perimetry (kinetic Goldmann and static Octopus, Haag-Streit), contrast sensitivity test (F.A.C.T., Stereo Optical) and microperimetry (Microperimetr MP-1, Nidek Technologies). The examined part of the central retina in microperimetric test was divided into four quadrants.

Results:

The Mean Sensitivity (MS) of central retina in the microperimetric test was the lowest in upper-nasal quadrant (Group 1 = 16,01 dB, Group 2 = 8,65 dB) and the highest in lower-temporal quadrant (Group 1 = 17,8 dB, Group 2 =14,33 dB) Also reduction in contrast sensitivity was observed which was more significant in the second group - Average Patch scores: for 1,5 Cycles/Degree - Group 1 = 5,08, Group 2 = 3,54; for 3 Cycles/Degree - Group 1 = 5,39, Group 2 = 3,64; for 6 Cycles/Degree - Group 1 = 4,79, Group 2 = 2,95; for 12 Cycles/Degree - Group 1 = 3,24 Group 2 = 1,92; for 18 Cycles/Degree - Group 1 = 2,12 Group 2 = 0,94; p<0,05.

Conclusions:

Microperimetry compared to other perimetric tests is a highly sensitive method for evaluating even the slightest changes in the sensitivity of the central retina. Microperimetry allows to detect changes in macular sensitivity, which may not be recorded by other perimetric tests. The relationship between the sensitivity of the central retina and the contrast sensitivity in patients with pituitary adenomas was observed. Microperimetry and contrast sensitivity testing as a non-invasive tests may provide additional tools to MRI in the diagnosis of optic pathway compression by pituitary adenomas. FINANCIAL INTEREST: NONE