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Use of combined biomechanical and tomographic data to detect keratoconus

Poster Details

First Author: E.Guilbert FRANCE

Co Author(s):    A. Saad   A. Grise-Dulac   H. Rouger   M. Humeniuk   D. Gatinel  

Abstract Details



Purpose:

To determine a new index using combined corneal biomechanical and tomographic data helping to detect keratoconus

Setting:

Fondation Ophtalmologique Adolphe de Rothschild, Paris, France

Methods:

Data of 213 eyes separated into two groups were retrospectively reviewed : normal (n=109) and keratoconus (n=104). Corneal hysteresis (CH), corneal resistance factor (CRF) and other biomechanical parameters were measured with an ocular biomechanics analyzer. Corneal thickness was measured using a combined placido-scanning slit system.

Results:

Using CH, CRF, H1, thinnest point and central corneal thickness, our index was able to discriminate normal cornea from keratoconus with a sensitivity of 96.2 % and a specificity of 90.8 %. ROC curve showed an area under curve of 0.967.

Conclusions:

Sensitivity and specificity of our new index combining biomechanical and tomographic data were high in detecting keratoconus. FINANCIAL INTEREST: NONE

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