Posters

Descemet's stripping endothelial keratoplasty (DSEK): early and late complication rates in 73 consecutive cases at a tertiary university hospital

Poster Details

First Author: N.Abdul Aziz UK

Co Author(s):    M. Rashid   P. Hossain           

Abstract Details

Purpose:

The purpose of this study is to describe the outcome and complications of DSEK surgery using manually dissected donor tissue at a tertiary university referral centre.

Setting:

University Hospital of Southampton NHS Trust, Southampton Eye Unit, Mailpoint 104, Tremona Road, Southampton, Hants, SO16 6YD

Methods:

A retrospective, consecutive case review of 100 eyes between 2007 and 2013. Main outcome measures included best corrected distance visual acuity (BDVA), post-operative manifest refractive spherical equivalence (MRSE), IOP elevation, and posterior graft dislocation, graft rejection, primary graft failure, and graft survival rates at 24 months.

Results:

The median age at the time of surgery was 74 years (LQ 65, UQ 80, range 37-92). Surgical indications included Fuch's dystrophy (64.4%), bullous keratopathy (34.3%) and other (1.4%). Sixty-six percent were pseudophakic and 34% were phakic eyes. Eighty-four percent had DSEK alone, 6% had repeat DSEK and 10% received a triple procedure. Raised IOP was the main complication (21.9%), followed by posterior graft dislocation (15.1%), graft rejection (6.8%) and primary graft failure (6.8%). Median LogMAR BDVA was 0.52 (LQ 0.36, UQ 0.75, range 0.12-1.90) and 0.40 (LQ 0.34, UQ 0.7, range 0.12-1.90) at 12 and 24 months, respectively. The average post-operative MRSE at last review was 0.5±1.4 D. Rate of graft survival at 24 months was 82%.

Conclusions:

The main complication observed at our centre was raised IOP. Posterior graft dislocation, graft rejection and primary graft failure rates were comparable to those reported elsewhere in the peer-reviewed literature. FINANCIAL INTEREST: NONE