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Validation of defocus tolerance of novel aberration-neutral hydrophobic acrylic monofocal IOL

Poster Details

First Author: V.Kolesnitchenko USA

Co Author(s):    A. Pilon                    

Abstract Details

Purpose:

To assess the refractive efficacy, accuracy to target and tolerance to defocus of aberration-neutral, hydrophobic acrylic monofocal (MX60, Bausch & Lomb) intraocular lens (IOL) technology when used to correct aphakia following cataract extraction in adults

Setting:

Multi-centered, clinical case series

Methods:

A multi-center, multi-surgeon, retrospective case series involving 125 eyes of 125 adult subjects with age-related cataract amenable to treatment with standard cataract extraction. Visual outcomes at 6 months (120-180 days post-op) were analyzed to determine uncorrected distance visual acuity (UCDVA), manifest refraction spherical equivalency (MRSE), absolute aim error (AAE), and assessment of UCDVA relative to MRSE

Results:

Collected values revealed mean UCDVA of 0.126±0.19 logMAR, mean MRSE of 0.054±0.56 D and AAE of 0.401±0.33 D. Refractive accuracy to target SE was found to be 44.26% of subjects within ±0.25D, 70.49% within ±0.50D and 95.08% within ±1.00D. Comparative analysis of UCDVA to MRSE diverged from the assumed impact increasing residual myopic MRSE is anticipated to have on resultant UCDVA (1 line reduction in visual acuity per -0.25D of uncorrected MRSE). LogMAR values stratified by residual MRSE were -0.027 (0.00 to -0.25D), 0.069 (-0.25 to -0.50D), 0.151 (-0.50 to -0.75D) and 0.363 (-0.75 to 1.00D), respectfully

Conclusions:

The aberration-neutral hydrophobic acrylic monofocal IOL evaluated demonstrated excellent refractive efficacy and accuracy in attaining refractive target. A unique feature that was validated during this study was this platform’s capacity to provide tolerance to defocus by allowing subjects to retain consistent UCDVA across a wide range of residual MRSE; a feature that may provide surgeon with more range of focus around their planned refractive target or a means to expand the range of monovision correction without sacrificing distance acuity

Financial Disclosure:

is employed by a for-profit company with an interest in the subject of the presentation

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