Posters

Possibilities of OCT-angiography in study of pathogenesis, diagnostics, and monitoring the macular telangiectasies in children

Poster Details

First Author: A.Starikova RUSSIA

Co Author(s):    N. Osipova   L. Katargina   E. Denisova   L. Kogoleva   A. Tarasenkov   M. Belova   O. Novikova  

Abstract Details

Purpose:

to assess the potential of OCT-angiography in studying pathogenesis, diagnosing and monitoring macular telangiectasias of various genesis in children and adolescents.

Setting:

The Helmholtz Moscow Research Institute of Eye Diseases of the Ministry of Health of the Russia, Moscow, 105062, Russia

Methods:

We examined and treated 5 children (6 eyes) aged from 10 to 17 years with idiopathic macular telangiectasias (3 eyes), developed against the background of Coat’s disease (1 eye) and diabetic retinopathy (2 eyes). The examination included standard ophthalmologic inspection, as well as optical coherence tomography (OCT) and OCT-angiography (OCTA). Two children underwent transpupillary laser coagulation of telangiectasias (2 and 3 sessions), two received an intravitreal injection of an inhibitor of angiogenesis. The parents of one child refused treatment.

Results:

According to OCTA, all children had pathological structural changes (microaneurysms, vascular artery abnormalities, changes in the density of the vascular pattern) of superficial and to a greater extent deep retinal capillary plexuses. As a result of the treatment, 3 children (4 eyes) had clinically noted decrease in the number of microaneurysms. According to OCTA, 2 children (3 eyes) showed a decrease in the number of microaneurysms in the superficial and especially in the deep plexus, and in a child with diabetic retinopathy there was also a slight increase in the vascular density of the deep capillary plexus.

Conclusions:

According to OCT-angiography, development of macular telangiectasias in children is accompanied by preferential changes in the deep capillary plexus, which indicates the pathogenetic significance of microcirculatory disturbances at this level. The method also reveals its value in monitoring the disease.

Financial Disclosure:

None