Posters

Effect of a hyaluronate-trehalose solution on ocular comfort and tear film instability after cataract surgery

Poster Details

First Author: Ö.Balta TURKEY

Co Author(s):                        

Abstract Details

Purpose:

To investigate the efficacy and safety of using of 3% trehalose and 0.15% sodium hyaloronic acid combination (Thealoz Duo) ophthalmic solution for ocular discomfort and tear-film stability in eyes after cataract surgery.

Setting:

Department of Ophthalmology, Dr. Nafiz Korez Hospital, Ankara, Turkey.

Methods:

This study included patients who underwent unilateral cataract surgery. After cataract surgery, the study group used topical antibiotic - steroid, 3% trehalose and 0.15% sodium hyaluronic acid combination, whereas the control group used only topical antibiotic – steroid. Preoperative, schirmer test was performed and tear breakup time (TBUT) was measured. Schirmer testi, TBUT, ocular surface disease index (OSDI), frequency of dry-eye symptoms evaluated using a visual analog scale (VAS), and corneal fluorescein staining were assessed postoperatively at 1 month .

Results:

The study included sevent-nine patients were randomly divided into study group and control group. There were no statistical differences in age, the difference of sex among the groups(p>0.05). There were no statistically differences Schirmer test scores and TBUT in the study group at the postoperative(p> 0,05), but there was a statistically significant decrease Schirmer test scores and TBUT in the control group(p<0,05). The OSDI scores, corneal fluorescein staining score, VAS Burning and stinging sensation and VAS foreign body sensation were lower in the study group compared to the control group at postoperative 1 month(p<0,05).

Conclusions:

3% trehalose and 0.15% sodium hyaloronic acid was effective and well tolerated in reducing dry-eye disease symptoms and improving the clinical outcome after cataract surgery.

Financial Disclosure:

None