Posters

360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2 year outcomes

Poster Details

First Author: T.Sato JAPAN

Co Author(s):    T. Kawaji   T. Mizoguchi   A. Hirata              

Abstract Details

Purpose:

Ab inerno trabeculotomy is one of minimally invasive glaucoma surgery. We have previously reported that 360° suture trabeculotomy ab interno (360SLOT ab interno) seemed to be effective for open angle glaucoma (OAG) in small samples and short term period (Clin Ophthalmol, 2015). In the present study, we examined the middle-term efficacy, safety, and risk factors of 360LOT ab interno for OAG.

Setting:

Prospective, non-comparative and non-randamized study at Sato Eye and Internal Medicine Clinic

Methods:

360SLOT ab interno alone was performed for patients with uncontrolled OAG, and 360SLOT ab interno with phacoemulsification was performed for controlled OAG with a visually significant cataract between March 2014 and September 2015, and the patients were prospectively followed for 2 years. Main outcomes were 2-year intraocular pressure (IOP), number of anti-glaucoma medications, postoperative complications, and predictive factors of surgical failure. Kaplan-Meier analysis was performed using criteria A (postoperative IOP ≤ 15 mmHg and IOP reduction ≥ 20%) and criteria B (IOP ≤ 12 mmHg and IOP reduction ≥ 30%). Predictive factors were evaluated using Cox proportional hazards ratios.

Results:

Sixty-four eyes of 64 patients were included, and 50 eyes (78%) of 64 eyes were followed–up for 2 years. Surgery significantly reduced IOP from 18.4 ± 2.9 mmHg before surgery to 13.4 ± 3.0 mmHg at 2-year after surgery (P < 0.001, paired t-test). Patients used an average of 1.8 ± 1.5 medications before surgery and 1.3 ± 1.5 medications at 2-year after surgery (P = 0.101, Mann-Whitney nonparametric test). No serious postoperative complications were observed. The probability of surgical success was 49.2% and 16.0% using criteria A and B, respectively. No surgical failure risk factors were identified.

Conclusions:

Nearly half of patients in the current study had a postoperative IOP ≤ 15 mmHg and IOP reduction ≥ 20% without serious complications at 2 years after surgery. 360SLOT ab interno procedure may be a useful option for treating mild- to moderate-stage of OAG.

Financial Disclosure:

None