Posters

Goniotomy with trabecular meshwork excision using the Kahook dual blade in severe and refractory glaucoma: six month outcomes

Poster Details

First Author: K.Mansouri SWITZERLAND

Co Author(s):    L. Salinas   A. Chaudhary   S. Dorairaj   J. Berdahl   G. Lazcano-Gomez   L. Seibold     

Abstract Details

Purpose:

To describe short-term efficacy and safety of goniotomy with trabecular meshwork excision using the Kahook Dual Blade (New World Medical Inc., Rancho Cucamonga, CA) in patients with severe or refractory glaucoma.

Setting:

Retrospective multicentric case series of 53 eyes with severe or refractory glaucoma as defined by ICD-10 conducted in the USA, Mexico and Switzerland.

Methods:

Primary efficacy outcome was a 20% or more decrease in intraocular pressure (IOP) from baseline at 6 months. Secondary efficacy outcome measures were probability of achieving an intraocular pressure 16 or 18 mm Hg at 6 months and the mean IOP change from baseline at 6 months. Medication use required to obtain target intraocular pressure (IOP) at last follow-up and adverse effects were analyzed.

Results:

The proportion of eyes achieving an IOP reduction of more than 20% from baseline at 6 months was 57.7% (n = 30). Mean IOP decreased from 18.4 ± 6.1 mm Hg at baseline to 13.9 ± 3.5 mmHg at month 6 (23.9% reduction, P < 0.001). At 6 months, 51.9% and 40.4% achieved an IOP 16 or 18 mm Hg, respectively, and the mean number of glaucoma medications was reduced by 1.2 ± 1.3 (36.6%) compared to baseline (P <0.001). The most common adverse event was blood reflux (n = 29, 34.9%). No severe complications were reported.

Conclusions:

Goniotomy with trabecular meshwork excision using the Kahook Dual Blade could be an alternative surgery for severe or refractory glaucoma, significantly reducing IOP and medication use at 6 months, with a low rate of complications.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a competing company