Posters

Analysis of optic nerve perfusion using angio-OCT in glaucoma

Poster Details

First Author: A.Hervas Ontiveros SPAIN

Co Author(s):    S. Garcia-Delpech   R. Diaz Cespedes   P. Udaondo   E. Sanz   A. Navarro   D. Salom   W. Furlan  

Abstract Details

Purpose:

To compare optic disc perfusion between normal subjects and subjects with glaucoma (mild, moderate, severe) using optical coherence tomography (OCT) angiography and to detect optic disc perfusion changes in glaucoma.

Setting:

The study was done at AIKEN clinic in Valencia (Spain) and in Hospital of Manises (Spain, Valencia)

Methods:

We studied 35 eyes of 20 patients (10 with glaucoma and 10 healthy controls) using Angio-OCT (AngioVue, Imex and Triton, Topcon). The total density of vessels by OCT-A (ONH) and the density of temporal vessels in the optic disc have been observed in both groups. Clinical data and evaluation of the spectral domain OCT (RNFL: thickness of the retinal nerve fiber layer, GCC: ganglion cell complex) were also evaluated.

Results:

In normal discs, a dense microvascular network was visible in angio-OCT, whereas this network was attenuated in all subjects with glaucoma. In the glaucoma group, the density of the total and temporal ONH vessels was reduced by 25% and 22% respectively, compared to the control group. Significant correlations were found between the total vascular density ONH and temporal density measured by OCT-A, the thickness of the retinal nerve fiber layer (RNFL), the ganglion cell layer (GCC) and the clinical parameters.

Conclusions:

Through angio-OCT, repeated measurements of the optic disc perfusion can be useful in the evaluation of glaucoma and its progression. More clinical investigations are necessary to confirm these promising results.

Financial Disclosure:

None