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Correlation between glaucoma and choroidal thickness measurement using enhanced depth imaging optical coherence tomography

Poster Details

First Author: H.Elsaied EGYPT

Co Author(s):    S. Galal   S. Esmat   M. Khafagy              

Abstract Details

Purpose:

To compare subfoveal choroidal thickness measurements in primary angle closure glaucoma (PACG), primary open angle glaucoma (POAG) patients, and normal age matched population, and to correlate between the subfoveal choroidal thickness with each of the average peripapillary retinal nerve fiber layer (RNFL) thickness, the average ganglion cell complex (GCC) thickness, as well as Humphrey field Analyzer parameters in these patients mainly the mean deviation (MD) and pattern standard deviation (PSD).

Setting:

Cairo university hospitals

Methods:

Cross sectional observational case-control study. The study included 124 eyes; 40 eyes of PACG patients, 42 eyes of POAG patients and 42 eyes of normal controls. Measurement of the subfoveal choroidal thickness was done using SD-OCT in the cross line scan.

Results:

No significant difference in subfoveal choroidal thickness among normal eyes, eyes with POAG and eyes with PACG (All P values > 0.05). There was a significant weak positive correlation between choroidal thickness and average RNFL thickness (r = 0.804, p value < 0.001). Thinner choroid was associated with older age (r = - 0.264, P value = 0.003) and myopic refraction (r = 0.243, P value = 0.007), while thicker choroid was related to a better visual acuity (r = 0.199, P value = 0.026). Also, there was no significant inter-observer variation for choroidal thickness measurements (P value = 0.161).

Conclusions:

Lack of a significant difference in subfoveal choroidal thickness among normal eyes, eyes with POAG and eyes with PACG. A significant positive correlation existed between choroidal thickness and average RNFL thickness.

Financial Disclosure:

None

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