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The clinical profile and features of 19 endogenous endophthalmitis cases

Poster Details

First Author: M.Shen CHINA

Co Author(s):    X. Shen   Y. Yuan   W. Ye   F. Yuan           

Abstract Details

Purpose:

To investigate etiological features and visual outcomes of endogenous endophthalmitis (EE).

Setting:

Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai 200032, China

Methods:

A prospective consecutive case series of 19 patients (23 eyes) presenting with presumed EE from 2009 to 2016 to the Ophthalmology Department of Zhongshan Hospital and Huashan Hospital, Fudan University were included. Patients’ history, microbial porfiles and visual outcomes were evaluated.

Results:

19 patients (23 eyes) were identified over the study period. Most patients underlay a relative immunosuppressive state. The major predisposing factors included diabetic mellitus(9/19) and liver abscess(8/19). Vitreous sample was cultured with a 12/20 microbial culture positivity, while 10/15 blood or bodily fluids positive. Candida albicans(5/6) was the most common pathogen isolated in fungal endophthalmitis, while Klebsiella pneumonia(7/13) in bacterial endophthalmitis. The visual acuities of only 5 eyes (29.41%) which were treated within one week were increased. A total of 6 out of 23 eyes were enucleated or eviscerated.

Conclusions:

Although EE has a low incidence, EE is a serious ocular condition and has poor visual outcomes. Early diagnosis and early treatment may be helpful for recovery of vision. However, ophthalmologists have to judge the timing of treatment of underlying diseases and EE. Multi-disciplinary team (MDT) may provide a better alternative for the treatment of EE.

Financial Disclosure:

None

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