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Accelerated corneal collagen cross-linking in progressive keratoconus: long-term results

Poster Details

First Author: M.Taskapili TURKEY

Co Author(s):    Y. Yildirim   B. Kepez Yildiz   A. Agca              

Abstract Details

Purpose:

To evaluate the long-term visual, refractive, and topographic outcomes of accelerated corneal collagen cross-linking (A-CXL) in the management progressive keratoconus.

Setting:

Beyoglu Eye Training and Research Hospital, University of Health Science,Istanbul,TURKEY

Methods:

Five hundred fifty six eyes of 342 patients with progressive keratoconus data were retrospectively reviewed. One hundred seventy eight eyes of 98 patients who intended accelerated (18 mW/cm(2), 365-nm ultraviolet-A light, 5 minutes) collagen crosslinking (CXL) included this study. Main outcome measures were change in keratometry, refractive status, uncorrected visual acuity (UCVA), and best-corrected visual acuity (BCVA) in five years follow up.

Results:

The mean age of all patients (48 women and 50 men) was 20.62 ± 5.6 years (range: 17 to 27 years). UDVA improved from 0.6 ± 0.4 to 0.56 ± 0.3 logMAR (P = .07) and CDVA improved from 0.52 ± 0.3 to 0.50 ± 0.29 logMAR (P = .06) at the postoperative five years visit. At the last follow-up visit, apex keratometry decreased from 58.60 ± 7.65 to 57.92 ± 6.42 D (P = .060) from baseline.

Conclusions:

The findings of this study revealed that A-CXL treatment effective and safe option in patients with progressive keratoconus in long term follow up.

Financial Disclosure:

None

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