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Selective transepithelial topography-guided photorefractive keratectomy with the LaserSoft solid-state 210 nm photorefractive laser platform combined with accelerated corneal collagen cross-linking

Poster Details

First Author: A.Nagpal INDIA

Co Author(s):                        

Abstract Details

Purpose:

To evaluate the changes in refractive outcomes and corneal aberrations after Selective transepithelial topography-guided photorefractive keratectomy with the LaserSoft solid-state 210 nm photorefractive laser platform combined with accelerated corneal collagen cross-linking (ACXL)

Setting:

Centre for Corneal Disease and Surgery & Wavelase Eye Centre, Ahmedabad, India

Methods:

12 eyes underwent selective topography-guided transepithelial PRK followed by accelerated CXL using riboflavin A and enhanced-intensity (9 mW/cm2, 7.2 J) ultraviolet light. Outcome parameters included uncorrected distance visual acuity (UCVA) and best spectacle corrected visual acuity (BSCVA). Corneal tomography and corneal wavefront aberrations were assessed before and 6 months after the procedure.

Results:

UCVA, BSCVA, sphere, cylinder, and simulated keratometry improved after treatment However, BDVA improved more in eyes with cone located within central 3mm. There was significant improvement in coma and corneal asymmetry aberration in eyes with cone located outside the central 3mm zone. Corneal wavefront Zernike aberrations changed but were not affected by cone location. No adverse effects was observed.

Conclusions:

213 nm topography-guided transepithelial PRK was easy to perform and well tolerated by patients. The combined LaserSoft PXL protocol demonstrated effective results in halting keratoconus progression improving corneal regularity with a safe and effective profile. It improved both visual acuity and corneal aberration in the mid-term period. Longer follow-up is need to confirm these results and observe long-term cxl flattening effect on the cone.

Financial Disclosure:

None

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