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Correlation of corneal biomechanics and confocal microscopy with corneal thickness in myopia

Poster Details

First Author: J.Titiyal INDIA

Co Author(s):    S. Verma   M. Kaur   T. Agarwal   R. Sinha   N. Sharma        

Abstract Details

Purpose:

To evaluate biomechanical and confocal microscopy (CM) changes in myopia and correlate with corneal thickness

Setting:

Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India

Methods:

Prospective evaluation of 204 eyes (102 patients) with myopia ≥ 0.5 D planned for laser refractive surgery. Eyes were divided on basis of thinnest pachymetry (CT) -group I: CT ≤500 μm, group II: CT >500 μm. Corneal hysteresis (CH), corneal resistance factor (CRF) and CM findings were evaluated.

Results:

Mean age was 22.78 ± 2.43 years. 57 eyes had CT ≤500 μm and 147 eyes had CT >500 μm. Group I had significantly lesser midstromal keratocyte density (SKD) (p=0.01), CH (p=0.01) and CRF (p=0.004) than group II. Corneal biomechanics (CH and CRF) significantly correlated with CT (r=0.45 & 0.36, p<0.001) and anterior SKD (r=0.4, p<0.001). There was poor correlation between magnitude of refractive error and CT

Conclusions:

Thinner corneas (≤500 μm) have suboptimal corneal biomechanics and keratocyte density as compared to thicker corneas

Financial Disclosure:

None

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