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Role of cutaneous leishmaniasis (CL) in immune stromal keratitis (ISK)

Poster Details

First Author: N.Osmani AFGHANISTAN

Co Author(s):    S. Hofiani                    

Abstract Details

Purpose:

To Describe the ISK after CL in two eye center in Afghanistan.

Setting:

1-NOOR Training Eye hospital which is a governmental hospital 2-Osmani Eye clinic which is a private clinic both located in Kabul Afghanistan.

Methods:

A descriptive study was conducted 2007 – 2015 and observed 230 ISK patients, their files and images of their leishmania lesion LL (scar) in outpatient ward of two eye centers (one public and one private) in Kabul Afghanistan. During this observation there were 165 patients with active ISK defined by stromal inflammatory infiltration mostly in contact with the limbus within 1 to 3 year of presentation. Identified the etiology of ISK by thorough ocular examination of the patients and medical and laboratory examinations.

Results:

Mean age M/A of participant were 19.52 years old y/o. M/A of getting CL was 9.52 y/o. 65.2% of the participants P were male and 34.8% of P female.95.7 % of the LLs on the face. 100%of LL were not active when ISK Dx. History of treating active LL were 39.1%Untreated,26.1% Incomplete medical treatment and traditional. 60.8% of P got CL between 5-7 y/o .ISK presentation 1,5-13 year after CL mean 7.25. ISK presentation 91.3% unilateral, 91.3% relapsed,30.4% relapsed in both eyes.

Conclusions:

100% of the CL were healed and mostly by body immune response, 100% of patients having leishmania Scar mostly on the face while diagnosed ISK, specific(limbo keratitis) ISK in all patients and the frequent relapses of ISK randomly alternating in both eyes supports that there is a strong relationship between ISK and CL. Recommend:Analytical studies for proving relationship between ISK and CL.

Financial Disclosure:

None

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