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Long-term outcomes of intraoperative triamcinolone injection vs postoperative oral prednisolone in congenital cataract surgery

Poster Details

First Author: B.Ventura BRAZIL

Co Author(s):    M. Zara   N. Caldas   L. Ventura   P. Marinho   M. Ventura        

Abstract Details

Purpose:

To compare surgical outcomes 8 years after congenital cataract surgery in which intraoperative intracameral triamcinolone or oral postoperative prednisolone was used to modulate ocular inflammation.

Setting:

Altino Ventura Foundation and HOPE Eye Hospital, both in Recife, Brazil

Methods:

This longitudinal cohort study was conducted between August 2016 and February 2017. All 60 patients (60 eyes) that participated in a previous clinical trial, which analyzed the 1-year surgical outcomes of congenital cataract surgery using intracameral triamcinolone (study group) or oral prednisolone (control group), were eligible to participate. The children underwent a complete ophthalmological exam. The main outcome measures were biomicroscopic findings, intraocular pressure (IOP), central corneal thickness (CCT), mean keratometry and foveal thickness.

Results:

Twenty-four patients presented for examination (Study group = 10 patients; control group = 14 patients). There was no statistically significant difference between the groups with regards to presence of posterior synechia, secondary visual axis obscuration, intraocular lens (IOL) coating, IOL decentration, IOP, CCT and mean keratometry (P > .05). However, the control group presented a thicker foveal thickness (P = 0,03). In both groups, there was a statistically significant increase in IOP and CCT 8 years after the procedure, when compared to the preoperative measurements and that obtained 1 year after surgery.

Conclusions:

Eight years after surgery, children operated of cataract and that received an intraoperative intracameral injetion of triamcinolone presented similar surgical outcomes to those that received postoperative oral prednisolone.

Financial Disclosure:

None

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