Posters

Ocular complications, visual outcomes, and surgical results in children with Marfan syndrome

Poster Details

First Author: S.Rezar-Dreindl AUSTRIA

Co Author(s):    E. Stifter   T. Neumayer   A. Papp   A. Gschliesser   U. Schmidt-Erfurth        

Abstract Details

Purpose:

To determine ocular complications in children with Marfan syndrom and evaluate the visual outcome in children with ectopia lentis.

Setting:

Children with Marfan syndrom who were referred for ophthalmological examination to the Department of Ophthalmology and Optometry, Medical University of Vienna.

Methods:

Seventy-six eyes of patients with genetically proved diagnosis of Marfan syndrom were retrospectively evaluated regarding ocular complications and visual acuity outcomes in ectopia lentis with or without lensectomy.

Results:

In 63% a subluxation of the lens was visible.54% of the patients with ectopia lentis received lensectomy. Mean follow-up of the patients with ectopia lentis was 3years.66% of the patients presented with myopia <-10diopters, 18% with >-10diopters.In patients with normal lens status(n=14) VA was 0.8±0.3/0.9±0.2, in patients with subluxation of the lens(n=24) VA was 0.5±0.3/0.5±0.3 at initial presentation(p<0.01).In children with subuxation of the lens without lensectomy(n=11) last VA improved from 0.5±0.3/0.5±0.3 to 0.7±0.3/0.7±0.2(p=0.08/0.3) at last follow-up.Patients who were referred to lensectomy with/without lens implantation VA improved from 0.5±0.3/0.5±0.3 to 0.6±0.3/0.7±0.2(p=0.2/0.03).

Conclusions:

In Marfan syndrome subluxation of the lens was found in the majority of the children. Good visual acuity results were observed in children with subluxation of the lens or following lensectomy.

Financial Disclosure:

None