Image quality metrics of an extended-depth-of-focus intraocular lens assessed in polychromatic light condition

Session Details

Session Title: Moderated Poster Session: EDOF vs Multifocal IOLs

Venue: Poster Village: Pod 1

First Author: : G.Labuz GERMANY

Co Author(s): :    P. Poompokawat   Y. Lee   G. Auffarth                 

Abstract Details

Purpose:

The optical quality of intraocular lenses (IOLs) is typically tested according to ISO-11979-2. This is an internationally-recognized guideline established to ensure high-quality standards for IOL manufacturing. However, its recommendation on the use of monochromatic light for image-quality testing can be criticized, as in real-world conditions the IOL functions in an optical system (the eye) that uses polychromatic light. This aspect of IOL functionality has become particularly relevant with the introduction of extended-depth-of-focus (EDOF) IOLs that provide chromatic-aberration correction, such as Symfony (Johnson&Johnson Vision). Therefore, in this study, we assessed the optical quality of Symfony IOLs in the polychromatic-light condition.

Setting:

David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of Heidelberg, Germany.

Methods:

We analyzed five Symfony IOLs, each having the same refractive power of 20.00D. A Trioptics OptiSpheric IOL PRO2 was used to perform optical testing. The nominal power was measured according to the ISO-11979-2 standard. The polychromatic-optical performance was assessed in a different set-up configuration, and that included a white-light source with a photopic-eye-response filter and a model cornea with spherical aberration. Chromatic aberration of a complete model eye without an IOL was 1.04D. An MTF-area, which was derived from the modulation-transfer function (MTF), was assessed with different apertures and ranges of defocus.

Results:

The mean nominal power (±SD) of the IOLs was 20.05±0.05D. The MTF area assessed at the far focus with a 2.0-, 3.0-, 4.0- and 4.5-mm pupil was 0.52, 0.48, 0.47 and 0.47, respectively, and at the best near focus it was, respectively, 0.59, 0.52, 0.45 and 0.43. The MTF area at a defocus value of +0.5D, 0D, -0.5D, -1.0D, -1.5D and -2.0D was 0.38, 0.48, 0.41, 0.38, 0.50 and 0.48, respectively. Photographs of the USAF resolution chart confirmed a satisfactory resolving power at the studied defocus range, particularly, at lower spatial frequencies.

Conclusions:

We demonstrated a good polychromatic MTF performance of the Symfony IOL at the far and near focus for all apertures with minimal pupil dependency. Moreover, the lens proved to be effective in correcting spherical aberration as the MTF-area levels were close regardless of the aperture size. The through-focus analysis showed an EDOF effect as the MTF area was 0.38 or more across all distances. The measured nominal power demonstrated low variability (with an SD of 0.05D) and was well below ISO tolerance limits (±0.4) for the nominal power.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, travel has been funded, fully or partially, by a competing company, travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, research is funded, fully or partially, by a competing company, research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, receives non-monetary benefits from a competing company., receives consulting fees, retainer, or contract payments from a competing company