Intraocular pressure and the component of metabolic syndrome in healthy young Koreans

Session Details

Session Title: Presented Poster Session: Glaucoma

Venue: Poster Village: Pod 2

First Author: : S.Lee SOUTH KOREA

Co Author(s): :    S. Kim   J. Lee   S. Lee                 

Abstract Details

Purpose:

To evaluate the relationship of intraocular pressure with component of metabolic syndrome in healthy young Korean population.

Setting:

Kosin University, College of Medicine, Department of Ophthalmology Busan, Korea

Methods:

A total of 7218 participants aged within third and forth decades have underwent automated multi-phasic test including tonometry, fundus photography, drawing up a questionnaires and measuring metabolic syndrome component variables such as waist circumference, systolic and diastolic blood pressure, high density lipoprotein, triglyceride and fasting blood glucose. Data were analyzed separately for men and women. Simple linear regression analyses and Multiple linear regression analyses were performed. Mean IOP was compared with the score according to the numbers of metabolic syndrome profile disturbance in men and women by ANOVA.

Results:

Final data consisted of 6559 subjects ( 5017 men and 1542 women) were investigated. In men, waist circumference, systolic and diastolic blood pressure, triglyceride and fasting blood glucose values have significantly positive relation with IOP. High density lipoprotein value has significantly negative relation. In multiple regression analysis, intraocular pressure have significant relation with waist circumference, systolic and diastolic blood pressure, and fasting blood glucose (p<0.05). In women, systolic and diastolic blood pressure, and fasting blood glucose values have significantly positive relation with IOP. In multiple regression analysis, intraocular pressure has significant relation only with systolic blood pressure (p<0.05).

Conclusions:

In men, positive relationship exists between IOP with the numbers of metabolic syndrome profile disturbances, and more metabolic syndrome components are associated with elevated IOP level. These findings indicate that modulating metabolic syndrome component variables may be necessary to help preventing elevated IOP level, especially in young korean men.

Financial Disclosure:

None