In vitro activity of moxifloxacin against conjunctival flora

Session Details

Session Title: Infections

Session Date/Time: Sunday 23/09/2018 | 16:30-18:00

Paper Time: 17:00

Venue: Room A3, Podium 3

First Author: : S.Edakhlon INDIA

Co Author(s): :    A. Kumar V   G. S.Pillai                 

Abstract Details

Purpose:

To study the in vitro activity of Moxifloxacin against conjunctival flora in patients undergoing cataract surgery.

Setting:

Comtrust Charitable Trust Eye Hospital, Thalassery, Kerala, India

Methods:

Conjunctival swab was taken from 480 patients who were posted for cataract surgery between November 2016 and February 2018 . Culture and sensitivity was done using these samples. Moxifloxacin resistance was studied in samples which grew bacteria.

Results:

181 samples grew Coagulase negative Staphylococcus of which 52 (28.72%) were resistant to Moxifloxacin , 39 samples grew Staphylococcus aureus of which 18 (46.15%) were resistant to Moxifloxacin.

Conclusions:

There is a high incidence of resistance to moxifloxacin in organisms grown from conjunctival sac. With such a high incidence of resistance, Moxifloxacin may not be a good choice antibiotic either as preoperative topical prophylaxis or as intracameral injection to prevent postoperative endophthalmitis.

Financial Disclosure:

-