Optical pathway imaging and stray-light evaluation of opacified intraocular lenses

Session Details

Session Title: IOL Dislocation & Opacification

Session Date/Time: Tuesday 25/09/2018 | 14:00-16:00

Paper Time: 15:30

Venue: Room A3, Podium 1

First Author: : H.Son GERMANY

Co Author(s): :    T. Yildirim   C. Choi   P. Merz   G. Labuz   G. Auffarth        

Abstract Details

Purpose:

IOL calcification is a serious condition that may degrade patients' vision. Despite its relatively low incidence rate, it may result in significant patient complaint and even IOL exchange. One of the main complaints that patients with opacified lenses report is the disturbing magnitude of photic phenomena such as glare caused by dispersion of incoming light rays that occurs at the site of opacification on lens surface. Therefore, in this laboratory study, we aimed to assess the scattering effects of five opacified lenses by qualitatively visualizing the ray propagation and quantitatively measuring the level of light scatter.

Setting:

The David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of Heidelberg

Methods:

Four explanted lenses were studied: Euromaxx ALI313Y(Argonoptics), Acri.Lyc44S(Acri.Tec), LS-312 MF30(Oculentis), and Adatomed 88TI(Adatomed). In addition, one IOL with artificially induced glistenings, PC-60AD(Hoya), and a control lens, CT ASPHINA 409(Carl Zeiss), were included. Each IOL was placed into a model eye on optical bench. Monochromatic green laser was projected through the lens. Images of optical pathway, made visible by fluorescein solution, were taken with a digital camera. Levels of straylight was measured using the C-Quant device (Oculus) adapted for in-vitro evaluation of IOLs. Measurements were performed at 7° scatter angle. Results were compared to those of an unopacified control lens.

Results:

All opacified lenses showed more light scatter visible as haze than the control lens. Each opacified lens showed its own characteristic ray propagation behaviour. Average straylight parameter (s) was 76.6±107.8deg^2/sr. Of the opacified lenses, highest straylight was observed in Euromaxx ALI313Y (s=289.71±14.3deg^2/sr), which exhibited granular depostis across its optic diameter, and least amount in Adatomed 88TI (s=18.7±1.3deg^2/sr), which showed central cluster-like opacification. Similar opacification pattern at optic center was seen in Acri.Ly44S with s=48.1±6.5deg^2/sr. In comparison, PC-60AD with glistenings had s=22.6±0.4deg^2/sr, while control lens showed least straylight (s=1.7±0.0deg^2/sr).

Conclusions:

We found that all of the opacified lenses showed higher straylight level than the unopacified control lens. The measured straylight parameter values could be confirmed qualitatively by means of observing the scattered optical pathway of the opacified lenses. The mentioned IOL opacifications appear to be significant sources of forward light scattering.

Financial Disclosure:

... receives consulting fees, retainer, or contract payments from a competing company, ... travel has been funded, fully or partially, by a competing company, ... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, ... research is funded, fully or partially, by a competing company, ... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, ... receives non-monetary benefits from a competing company., ... receives non-monetary benefits from a company producing, developing or supplying the product or procedure presented.