Perioperative risk factors for the development of cystoid macular edema after cataract surgery: an updated report from the ESCRS PREMED study

Session Details

Session Title: Cataract Surgery Special Cases

Session Date/Time: Tuesday 25/09/2018 | 08:00-10:00

Paper Time: 09:36

Venue: Room A3, Podium 1

First Author: : C.Veldhuizen THE NETHERLANDS

Co Author(s): :    C. Veldhuizen   L. Wielders   J. Schouten   F. van den Biggelaar   B. Winkens   R. Nuijts     

Abstract Details

Purpose:

To identify and assess perioperative factors influencing the risk of developing cystoid macular edema (CME) after cataract surgery in both diabetic and non-diabetic subjects.

Setting:

The European Society of Cataract and Refractive Surgeons (ESCRS) PREvention of Macular EDema after cataract surgery (PREMED) study is a European multicenter randomized controlled trial (RCT) investigating the optimal prevention of CME after cataract surgery.

Methods:

This study investigates possible perioperative risk factors for developing clinically non-significant and clinically significant cystoid macular edema (CSME). Risk factors assessed included the experience of the surgeon (qualified ophthalmologist vs. trainee status), whether or not femtosecond laser-assisted cataract surgery (FLACS) was performed, and whether a hydrophobic or hydrophilic intraocular lens (IOL) was implanted. Logistic regression with correction for preventative strategy was separately applied to each potential perioperative risk factor. A Fisher’s exact test was used for diabetic subjects due to small number of subjects who developed CME.

Results:

Preliminary results suggest that for both diabetic and non-diabetic subjects, surgeon experience, FLACS, and IOL material are not statistically significant risk factors for developing CME and CSME at 6 weeks after cataract surgery. Similar conclusions were obtained after correcting for PREMED preventative treatment interventions.

Conclusions:

Based on our updated preliminary results of the ESCRS PREMED study, we found no statistically significant perioperative risk factors for CME and CSME at 6 weeks after cataract surgery in both diabetic and non-diabetic subjects.

Financial Disclosure:

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