Evaluation of iridocorneal angle, choroidal thickness, and retinal nerve fiber layer thickness in children with history of retinopathy of prematurity

Session Details

Session Title: Anterior Segment Imaging I

Session Date/Time: Monday 24/09/2018 | 16:30-18:00

Paper Time: 16:48

Venue: Room A4

First Author: : M.Ulusoy TURKEY

Co Author(s): :    S. Kivanc                    

Abstract Details

Purpose:

Preterm birth crucially changes the infant’s environment, which could lead to breakdown of normal ocular development and function. Retinopathy of prematurity (ROP) is a proliferative retinopathy affecting premature infants, which is characterized by abnormal maturation of the retinal vasculature. We aimed to evaluate iridocorneal angle, choroidal thickness and retinal fiber layer thickness of the children that have a history of retinopathy of prematurity using spectral domain optical coherence tomography (SD-OCT).

Setting:

This retrospective study was designed and performed at ophthalmology department of Başkent University, School of Medicine, Konya Research Hospital.

Methods:

Fifty eyes of 28 children with prematurity history and 46 eyes of 23 healthy school-aged childen were included in this study. Retinal nerve fiber layer thickness (RNFLT), choroidal thickness and iridocorneal angle parameters (trabecular-iris angle (TIA), angle opening distance (AOD500) and trabecular-iris space area (TISA500) 500 μm from the scleral spur) were evaluated using SD-OCT. Student’s t test was used according to the Kolmogorov Smirnov test results. Correlations between the variables were investigated based on the Pearson or Spearman correlation coefficient.

Results:

Subfoveal (ROP: 253.98±42.5, control:286.2±71.9, p=0.045), 500µ (ROP:242.04±41.8, control:276.7±45.3, p=0.003), 1000µ (ROP:237±39.7, control:270.15±55.93, p=0.007) and 1500µ (ROP:224.16±37.5, control:259.75±55.2, p=0.003) temporally choroidal thicknesses were significantly thinner in ROP history children. None of the rnfl thickness parameters and ganglion cell complex thickness were different between groups. Iridocorneal angle parameters were significantly lower in children with ROP history. (TIA: ROP=31.35±3.9 degrees, control=35.4±4.5 degrees, p<0.001; TISA500: ROP=0.167±0.05 mm2 , control=0.21±0.05 mm2 , p=0.003; AOD500: ROP=480.96±160.4µm , control=542.95±161.2 µm, p=0.035)

Conclusions:

Differences in iridocorneal angle of the preterms, show us, prematurity can affect development of various part of eye. In addition theese children should be follow for possible iridocorneal angle pathologies.

Financial Disclosure:

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