Image registration demonstrates central lens thickness minimally changes during accommodation

Session Details

Session Title: Vision & Accommodation Assessment

Session Date/Time: Monday 24/09/2018 | 14:00-16:00

Paper Time: 14:48

Venue: Room A3, Podium 2

First Author: : A.Grzybowski POLAND

Co Author(s): :    R. Schachar   M. Gaca-Wysocka   I. Schachar   F. Kamangar   B. Pierscionek        

Abstract Details

Purpose:

The purpose was to determine the changes in anterior chamber depth (ACD) and central lens thickness (CLT) during pharmacologically induced accommodation.

Setting:

This was a prospective study of healthy volunteers at the Department of Ophthalmology, Poznan City Hospital, Poznan, Poland.

Methods:

Following pupillary dilation with phenylephrine 10%, baseline auto-refractions and swept-source optical coherence tomographic biometric images were obtained from right eyes of 25 subjects aged 19 to 24 years. Pilocarpine 4% and phenylephrine 10% were instilled into these right eyes. One hour later, auto-refractions and biometric imaging were repeated. Only data from eight of 25 subjects met the following stringent criteria to be included in the study analysis: pre and post-pilocarpine biometric foveal images were registerable, images of the corneal centers were shifted by ≤100 μm, pupils >5 mm and pharmacologically induced refractive change ≥−7 diopters.

Results:

The mean auto-refractive accommodative change for the eight included subjects was −12.45 diopters (± 3.45 diopters). The mean change in CLT was 81 μm (± 54 μm) and the mean change in ACD was −145 μm (± 86 μm). Superimposition of the registered pre and post-pilocarpine biometric images of the sagittal sections of the whole eye from each subject demonstrated that the position of the whole lens did not shift either anteriorly, posteriorly or vertically during pharmacologically induced accommodation.

Conclusions:

A small increase in lens thickness was associated with a large change in accommodative amplitude and no significant change in lens position as predicted by the Schachar theory.

Financial Disclosure:

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