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Optical design and performance of a novel monofocal extended-depth-of-focus intraocular lens

Poster Details

First Author: M.Packer USA

Co Author(s):    K. Venkateswaran   N. Tiwari   S. Young              

Abstract Details

Purpose:

To describe the optical modeling, laboratory results and predicted clinical performance of the Mono-EDoF IOL Model ME4 (Advanced Vision Science, Santen, Inc., Goleta, California), a novel monofocal extended depth of focus IOL designed with a single broadened modulation transfer function (MTF) peak meeting the ISO 11979-2 monofocal optical standard.

Setting:

Advanced Vision Science, Goleta, California, USA Tatvum Research Optics Laboratory, Orange County, California, USA

Methods:

A model eye with an ISO model cornea optically coupled with a CCD camera was used to simulate retinal images of real-world polychromatic objects under photopic and mesopic conditions.

Results:

Mono-EDoF IOL Model ME4 demonstrated at least 1.25 D depth of focus.  Quantitative and qualitative image analyses performed with images obtained using 3.0 mm and 4.5 mm apertures, representing photopic and mesopic pupil sizes, respectively, demonstrate that the Mono-EDoF IOL Model ME4 has distance image quality similar to a monofocal IOL and intermediate image quality superior to a monofocal IOL. At the same time, the Mono-EDoF IOL Model ME4 exhibits fewer photic phenomena, including halo and glare, compared to conventional extended depth of focus IOLs.

Conclusions:

The novel optical design of the Mono-EDoF IOL Model ME4 demonstrates an extended range of vision from distance to intermediate with minimal photic phenomena. The Mono-EDoF IOL Model ME4 meets the ISO standard for a conventional monofocal IOL yet improves the range of vision to increase spectacle independence in the intermediate range without compromising distance vision. It is expected that the clinical performance of the Mono-EDoF IOL Model ME4 will be superior in terms of providing superior image quality at intermediate distances while reducing optical design related photic phenomena.

Financial Disclosure:

... gains financially from product or procedure presented, ... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, ... receives consulting fees, retainer, or contract payments from a competing company, ... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, ... is employed by a for-profit company with an interest in the subject of the presentation, ... has significant investment interest in a company producing, developing or supplying product or procedure presented

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