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Comparison of central corneal thickness with ultrasound pachymetry, non-contact specular microscopy and spectral domain optical coherence tomography in children

Poster Details

First Author: S.Karaman Erdur TURKEY

Co Author(s):    G. Demirci   F. Dikkaya                 

Abstract Details

Purpose:

To determine the agreement of central corneal thickness (CCT) measurements taken with ultrasonic pachymetry (USP), spectral domain optical coherence tomography (SD-OCT) and non-contact specular microscopy (NSM) in children.

Setting:

Istanbul Medipol University.

Methods:

A prospective, observational, cross-sectional study was performed in the outpatient ophthalmology clinic. CCT was measured in a total of 167 eyes of 167 consecutive healthy children with USP, NSM and SD-OCT. All examinations were performed by the same examiner. Bland–Altman plots were used to evaluate the agreement between instruments.

Results:

The average CCT values obtained by USP, NSM and SD-OCT were 565±37µm, 564±34 µm and 556±34 µm, respectively. There was a strong correlation between instruments:  USP with SD-OCT (r=0.937, p<0.01), USP with NSM (r=0.943, p<0.01) SD-OCT with NSM (r=0.975, p<0.01) for CCT. The mean differences (lower/upper limit of agreement) for CCT measurements were -10 ± 12.9 µm (15.28/-35.28) between SD-OCT and USP, -8.1 ± 7.7 µm (7/-23.2) between SD-OCT and NSM, and 1.8 ± 12.3 µm (25.9/-22.3) between USP and NSM.

Conclusions:

USP and NSM were found to have comparable CCT measurements and these two methods can be used correspondingly. However, CCT measurements by SD-OCT were lower when compared to other methods.

Financial Disclosure:

None

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