Posters

Sub-conjunctival and lacrimal gland injection with platelet-rich plasma (E-PRP) in treating chronic unresponsive dry eye disease

Poster Details

First Author: O.Abdalrahman SPAIN

Co Author(s):    A. Rodríguez   J. Alió                 

Abstract Details

Purpose:

To evaluate the effectiveness of injecting autologous platelet rich plasma (PRP) sub-conjunctival and in the lacrimal gland for treating chronic unresponsive dry eye disease and increasing lacrimal glands tear production.

Setting:

This new therapeutic approach was carried at Vissum Instituto Oftalmologico de Alicante, University Miguel Hernandez, Alicante, Spain.

Methods:

A prospective, interventional case series design on 12 patients (10 females and 2 males) have been diagnosed as keratoconjunctivitis sicca where all have been injected once with 1 ml of concentrated PRP plus 60-70 µl calcium chloride in the lacrimal gland and sub-conjunctiva. All patients have been experienced tear film evaluation tests (dry eye protocol); Schirmer test, tear break up time test (TBUT), corneal staining according to oxford classification and OSDI before and after injection.

Results:

All patients have shown significant improvement in Schirmer test value from 0.7±2.1 to 9.6±1.4, TBUT value from 5±0.5 to 11±1.4 s and decrease in ocular surface staining and ocular discomfort after PRP injection.

Conclusions:

Injecting PRP in the lacrimal gland and sub-conjunctival is a safe, effective and promising procedure in treating chronic unresponsive dry eye by increasing the quantity and the quality of lacrimal glands’ tear production with absence of any side effects or complications.

Financial Disclosure:

None