Posters

Comparative evaluation of the use of platelet-rich plasma in pterygium surgery

Poster Details

First Author: O.Vasilyeva RUSSIA

Co Author(s):    Y. Evstigneeva   V. Kurenkov   S. Aksenova              

Abstract Details

Purpose:

To evaluate the results of surgical treatment of pterygium in the classical way in comparison with the use of platelet-rich plasma (PRP).

Setting:

LLC “Dr. Kurenkov Eye Clinic”

Methods:

20 patients(25 eyes)with the diagnosis of pterygium II-III degree were observed, including 14women(60.9%)and 9men(39.1%). The average age was58.7±7years. Patients were divided into three equal groups. The comparison group(10 eyes)underwent the classical pterygium surgery by McReynolds. The control group №1(7 eyes)underwent pterygium surgery, supplemented with subconjunctival PRP injection under the pterigium body. The control group №2(8 eyes)underwent pterygium surgery, subconjunctival injection of PRP, and the plasma supernatant above the PRP as instillations in the first 7days.Patients were prescribed: visual acuity test, optical coherence tomography(OCT), photo-registration before, 7days and 1month after surgery, also-coagulogram of venous blood before surgery. The follow-up period:6-12months.

Results:

In comparison group,total epithelization time of corneal wound was5.6±0.92days, which was monitored by biomicroscopy and OCT of the anterior segment. Also,during the first3±1days, patients presented severe complaints of corneal syndrome(3.8±1.23points on a five-point scale). In control group№1 complete corneal epithelization was during4.7±0.76days, corneal complaints were mild(3.14±1.57points). In control group№2 epithelization time was4.25±0.7days, the severity of corneal syndrome was estimated at3±1.07points. Evaluation of pterygium relapse in 6months after surgery: in comparison group the relapse was observed in 2eyes, in control group №1 there were no relapses, in control group №2–in 1eye.

Conclusions:

The use of PRP in addition to the classical pterygium surgery allowed to reduce the period of postoperative recovery and the severity of corneal syndrome in the early postoperative period. Moreover,in patients, where pterygium surgery was supplemented with subconjunctival injection of PRP and instillations of supernatant plasma, the decrease of these indices was significant(p<0.05). Also,due to the positive effect of PRP-technology on the severity and duration of early postoperative period, the number of relapses in patients in control groups was objectively less than in comparison group. So,the use of PRP as a way to improve pterygium surgery is possible.

Financial Disclosure:

None