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Straylight measurement in patients with fish-eye disease: a case series

Poster Details

First Author: K.Vasanthananthan NETHERLANDS

Co Author(s):    I. van der Meulen   R. Lapid-Gortzak   T. van den Berg              

Abstract Details

Purpose:

To investigate visual complaints in patients with fish eye disease (FED) with good visual acuity by examining straylight values and to evaluate these patients after surgical treatment.

Setting:

Department of Ophthalmology, Amsterdam University Medical Center, the Netherlands

Methods:

A single-center consecutive case series of 7 patients (male 3, female 4; mean age 49.7 SD 16,1 years) with fish eye disease were examined with visual acuity measurements, straylight and slit lamp examination. One patient had undergone a deep anterior lamellar keratoplasty (DALK) in both eyes, and one patient had undergone a penetrating keratoplasty (PKP) and cataract extraction in one eye.

Results:

Straylight was strongly elevated (up to 24x) and visual acuity was relatively well preserved (Snellen vision 1.16; range 0.8-1.6). Surgical intervention with both PKP and DALK lead to significant reduction of straylight values with improvement of the visual complaints. After PKP and DALK straylight levels return to normal, the latter depending on the amount of residual corneal stromal tissue. Eight years postoperatively, no signs of recurrence of fish eye disease in the graft were noted. During follow-up (mean 32 SD 16.6 months) of three patients, with no surgical intervention, the straylight values increased in different rates.

Conclusions:

The FED patients in this study had highly elevated straylight, despite maintaining nearly normal visual acuity. Straylight measurements can support clinical decision-making by quantifying complaints about reduced visual quality. For cataract logMAR + log(s) = 1.5 has been proposed as indication value to consider surgery, but for corneal transplantation a higher upper value seems more likely. Corneal transplantation may lead to good clinical results. Long term follow-up revealed no recurrence of the disease in the graft (n=2).

Financial Disclosure:

None

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