Posters

New era of lens biophysical quantification with high-speed swept-source OCT: a lens biophysics model

Poster Details

First Author: K.Singh INDIA

Co Author(s):    R. Shetty   A. Sinha Roy   G. Kundu              

Abstract Details

Purpose:

To introduce and identify novel features of lenticular accommodation using high speed swept source optical coherence tomography (OCT) and to study real time dynamic Accommodation aberrometry with pyramidal aberrometry.

Setting:

Narayana Nethralaya Eye Hospital,Bangalore,India

Methods:

50 patients were imaged on high speed swept source OCT using an accommodative stimulus ranging from 0 to -4D and lens morphological changes were noted. Real time Dynamic accommodation aberrometry was recorded in 50 patients undergoing refractive surgery and 25 patients of keratoconus (mild to moderate grade). Lens accommodation in relation to cornea astigmatism and aberration was analysed.

Results:

Anterior chamber depth(ACD) measured on inducing accommodative stimulus from 0 to -1D, increased from 3.39mm to 3.51mm but normalized to 3.4 mm on reaching -4D stimulus. Lens thickness increased from 3.78 mm to 3.93 mm by -4D stimulus. In 60 % of the eyes, dynamic aberrometry study group, corneal cylinder was internally compensated for by the lens. The remaining 40% eyes did not show appropriate compensation resulting in poor acceptance of cylinder component of refractive correction. Lens also compensated for corneal coma and spherical aberration in keratoconic eyes. 6% patients had excessive accommodation which induces myopic shift and irregular accommodation.

Conclusions:

OCT imaging and dynamic aberrometry were extremely useful in understanding lens biophysics. This unique model helped us decode the interaction between the lens and the cornea. Comprehending these concepts will have a huge impact in the future planning of customized refractive treatments, ICL implantation and developing newer generation Intraocular Lens (IOL) Formulae

Financial Disclosure:

None