Posters

Changes of crystalline lens during accommodation evaluated by anterior segment optical coherence tomography

Poster Details

First Author: Y.Kusumi JAPAN

Co Author(s):    Y. Suzuki   T. Mitsukawa   C. Shigeyasu   N. Matsuki   M. Yamada        

Abstract Details

Purpose:

Understanding the behavior of crystalline lens during accommodation that causes optic change is essentially important. Advances in anterior segment optical coherence tomography (AS-OCT) have enabled the detailed biometry from the corneal surface to the whole lens. This study was undertaken to analyze the changes of ocular biometric components (OBCs) at different accommodative demands using AS-OCT technique.

Setting:

A cross sectional study at the ophthalmology department, Kyorin University School of Medicine, Japan.

Methods:

Twenty healthy volunteers (7 males and 13 females; aged 22–34 years), who had no history of eye disease except for refractive errors, were recruited. The OBCs including anterior chamber depth (ACD), lens thickness (LT), anterior and posterior curvature of lens (ACL and PCL) were measured using AS-OCT (CASIA2, TOMEY, Japan). The measurements were done at 3 different accommodative demands (none, 3 diopters, and 5 diopters). The same tests were repeated after topical administration of 1% cyclopentolate or 0.5% tropicamide.

Results:

Changes in these parameters at accommodative demands were evaluated through AS-OCT observation. The ACD and ACL decreased at accommodative demands in a dose-dependent manner (ACD: 3.17±0.23 mm to 3.03±0.25 mm, ACL: 11.97±1.46 mm to 9.41±1.62mm), whereas PCL did not show significant changes. The LT increased in response to accommodative demands (3.73±0.26 mm to 3.90±0.28 mm). After topical administration of cycloplegic eyedrops, changes in ACD, ACL, and LT extinguished regardless of accommodative stimuli.

Conclusions:

According to our results, AS-OCT is capable of detecting the behavior of crystalline lens during accommodation. The main mechanism of accommodation appears to be derived from the bulge of anterior portion of the lens. AS-OCT may be a powerful tool for objective evaluation of accommodation.

Financial Disclosure:

None