Posters

Analysis of glaucoma progression detection by optical coherence tomography and visual field

Poster Details

First Author: K.Randelovic CROATIA

Co Author(s):    K. Novak Laus   M. Zoric Geber   Z. Vatavuk              

Abstract Details

Purpose:

To compare the detection and rates of progressive retinal nerve fiber layer (RNFL) loss with spectral-domain (SD) OCT and visual field loss using Global Trend Analysis (Octopus 900 Haag –Streit International Visual Field Analyser) in glaucomatous eyes classified by modified Hodapp-Parrish grading scale.

Setting:

University Hospital Center „Sestre milosrdnice“, Department of Ophthalmology, Vinogradska cesta 29, Zagreb, Croatia.

Methods:

In retrospective cohort study glaucoma patients were included with at least 2 years of follow up and minimum of 4 SD-OCT and 5 reliable VF examinations. Rates of RNFL and VF loss were calculated, and progression estimates were compared using generalized estimating equations and McNemar's tests.

Results:

A total of 40 eyes of 20 patients (mean age 67.8±6.4 years) were included with mean follow-up of 60.64±12.22 months. Overall, 12 of 40 eyes (30%) showed RNFL progression, and 6 eyes (15%) showed VF progression. Eyes with mild glaucoma showed significantly more progression on SD-OCT compared with VF (P<0.001). RNFL and VF progression showed faster rates of loss in average RNFL, inferior RNFL, compared with VF mean deviation.

Conclusions:

SD-OCT progression was significantly more common than VF progression in glaucomatous eyes classified with early and severe disease. Structure and fuction should be monitored closely across the entire spectrum of glaucoma severity.

Financial Disclosure:

None