Posters
Preliminary clinical results of CO2 laser-assisted sclerectomy surgery (CLASS) in Chinese patients with advanced primary open-angle glaucoma
Poster Details
First Author: J.Liu CHINA
Co Author(s): N. Sun
Abstract Details
Purpose:
To evaluate the efficacy and safety of CLASS in Chinese patients with advanced primary open-angle glaucoma.
Setting:
CLASS (CO2 laser-assisted sclerectomy surgery) is a nonpenetrating filtration surgery by using CO2 laser.Observe effects of open angle glaucoma (POAG) patients underwent CLASS at the Ophthalmology Department, Xi’an No. 4 Hospital, from Nov 2018 to Jan 2019.
Methods:
11 eyes of 10 Chinese patients (18y old or older, C/D ratio≥0.8) with medically uncontrolled advanced primary open angle glaucoma (POAG) underwent CLASS at the Ophthalmology Department, Xi’an No. 4 Hospital, from Nov 2018 to Jan 2019. IOP of all patients is higher than 21mmHg with at least 3 IOP-lowering medications. Patients underwent YAG laser peripheral iridectomy (LPI) in preoperative CLASS by the same surgeon. Complications, IOP, visual acuity, and number of medications were observed at baseline and post-operation.
Results:
The mean age was 47.09士11.84 years. The mean IOP of total eyes is 24.88士6.05mmHg with 3.63士0.56 IOP-lowering medications, with 0.9士0.05 C/D ratio. The mean IOP of post-1 day, 1 month, and 2 month significantly dropped to 7.53士2.42 mmHg, 8.50士0.83 mmHg, and 14.67士3.48 mmHg respectively (P＜0.01). Complete success rate is 90.91% at post-3 month. The visual didn’t significantly change. Shallow anterior chamber occurred in 3 cases,recovered without any treatment. 3 cases performed additional LPI at post-1 week.
Conclusions:
Conclusion: CLASS operation could reduce IOP effectively in managing Chinese advanced primary open-angle glaucoma. Preoperative LPI is necessary for preventing peripheral anterior synechia (PAS). Fibrosis of surgical zone and PAS both play important role in failure of CLASS operation. MMC should be used in younger patients. Postoperative additional LPI is needed in some patients. However, clinical observation of more cases with longer follow-up time are necessary.
Financial Disclosure:
None
