Posters

Evaluation of optic disc cup surface depression rate in glaucoma patients

Poster Details

First Author: R.Figueiredo PORTUGAL

Co Author(s):    T. Morais-Sarmento   J. Garrido   J. Carvalho   A. Rebelo   A. Candeias        

Abstract Details

Purpose:

To evaluate the utility of optic disc cup surface depth measurement using spectral-domain optical coherence tomography (SD-OCT) and compare its depression rate with retinal nerve fiber layer (RNFL) thinning in glaucoma patients’ follow-up.

Setting:

Hospital do Espírito Santo de Évora, Évora, Portugal.

Methods:

Retrospective longitudinal study in which 65 eyes from 65 patients with mild glaucoma (mean deviation [MD] better than -6 dB) and 30 eyes from 30 patients with moderate-severe glaucoma (MD worse than -6 dB) were included. Mean follow-up was 6.28±1.92 years in the mild glaucoma group and 5.80±1.56 years in the moderate-severe group. The Optic Disc Cube 200x200 protocol scans of Cirrus HD-OCT® were used and the mean cup surface depth was calculated using the formula: Cup Volume/(Disc Area x Average Cup-to-disc Ratio2) – 200 µm.

Results:

Albeit without statistical significance, the rates of mean cup surface depression were greater in mild glaucoma than in moderate-severe glaucoma (-1.24±3.27 µm/year vs -0.45±2.94 µm/year, respectively; p=0.259). Mean rates of percentage change in cup surface depression were significantly greater than the mean rates of percentage change in RNFL thinning in mild glaucoma (-2.44±7.39 %/year vs -0.24±0.90 %/year, respectively; p=0.034) but not in moderate-severe glaucoma (-0.29±2.19 %/year vs -0.24±1.10 %/year, respectively; p=0.829).

Conclusions:

Mean cup surface depth appears to change faster than RNFL thickness in mild glaucoma patients. Further studies are required to evaluate its usefulness in monitoring glaucoma progression before significant RNFL changes are detected in SD-OCT.

Financial Disclosure:

None