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Long-term results of different glaucoma surgery procedures with implantation of porous collagen implant

Poster Details

First Author: L.Arutyunyan RUSSIA

Co Author(s):    S. Anisimova   S. Anisimov                 

Abstract Details

Purpose:

To investigate the long-term effectiveness of intraocular pressure (IOP) and medication (meds) reduction in patients who have undergone different glaucoma surgery procedures  with implantation of collagen drainage (CD).

Setting:

Eye Center «East Sight Recover», Moscow, Russia.

Methods:

The patients with advanced stages of primary open-angle glaucoma (POAG) and secondary glaucoma (pseudoexfoliative, pigmentory) treated with different glaucoma surgery procedures and implantation of CD were included in the study. Follow-up period was 6 months, 1, 2, 3, 4 and 5 years. Main outcomes were intraocular pressure, medication burden. Secondary outcomes were visual acuity, corneal hysteresis (CH), parameters of visual field (VF) analysis (mean defect, pattern standard deviation), retinal nerve fiber layers thickness and optic disk morphology changes registered with the optical coherence tomography (OCT).

Results:

71 patients (71 eyes) with mean age 73.1±7.92 had diagnosis of progressive POAG or secondary glaucoma. Average IOP was 27.7±7.9 and average meds was 2.1±0.83. At 6 months, 1, 2, 3, and 4 years, average IOP was 14.9±3.3, 15.3±4.0, 14.2±3.8, 15.2±3.3 and 15.5±3.3 respectively.  By the end of 5 years, the level of normalized IOP was observed in 20.9% of patients without meds, in 68.1% of patients 1.7 ± 0.8 average meds was required. Stabilization of the glaucomatous changes was detected in 56 patients (78.9%) at 5-years follow-up that was confirmed with the VF and OCT examination.

Conclusions:

In conclusion, non-penetrating deep sclerectomy with collagen drainage implantation Xenoplast is an effective procedure to normalize the level of IOP, stabilize the glaucomatous changes and decrease the number of medications needed for glaucoma control.

Financial Disclosure:

None

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