Posters

Two-year outcome of topography-guided photorefractive keratectomy with collagen cross-linking for keratoconus

Poster Details

First Author: J.Tan CANADA

Co Author(s):    S. Holland   A. Covello   S. Arba Mosquera   V. Shwetabh   J. Hodgen   J. Tan     

Abstract Details

Purpose:

To evaluate 24 months results of topography-guided Photorefractive Keratectomy (TG-PRK) with simultaneous collagen cross-linking (CXL) for keratoconus.

Setting:

Laser Eye Centre

Methods:

Retrospective consecutive series of keratoconic eyes were studied to evaluate the outcomes of Topographic Guided Photorefractive Keratectomy (TG-PRK) with the Schwind Amaris 1050 Excimer laser with simultaneous corneal collagen cross-linking (CXL). Image capture with Sirius and CXL with the Athens protocol. Pre-operative and post-operative uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction (MR) and topographic data were analyzed. Cases with sufficient data at 24 months follow-up were included.

Results:

88 eyes had sufficient data at 24 months for analysis. 50 of 88 (57%) showed UDVA ≥20/40 post-operatively.  36 eyes (41%) had improved CDVA and 20 (23%) gained two or more lines while 22 eyes (25%) had loss CDVA with 8 (9%) lost 2 lines or more. Mean astigmatism was reduced from 2.83±1.81D to 1.82±1.64D (p<0.0001). Mean spherical equivalent was improved from -3.46±3.65D to -0.52±2.14D (p<0.0001). 4 eyes showed progression and 5 with haze judged sufficient to reduce CDVA.

Conclusions:

Two year results of topography-guided PRK (Schwind Amaris) treatment with CXL for keratoconus show efficacy and safety, with more than half achieving 20/40 UDVA or better. 41% had improved CDVA and almost a quarter had CDVA improved two or more lines. It provides an alternative to contact lens intolerant keratoconus patients.

Financial Disclosure:

... is employed by a for-profit company with an interest in the subject of the presentation, ... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented