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Evaluation of contrast sensitivity, visual acuity, twilight vision, endothelial microscopy and corneal topography in patients with keratoconus following corneal cross-linking

Poster Details

First Author: I.Krolo CROATIA

Co Author(s):    A. Kasumović   I. Radman   M. Malenica Ravlić   Z. Vatavuk   K. Lončarić        

Abstract Details

Purpose:

To assess the visual function with contact lenses (CLs) in keratoconus patients as well as the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), twilight vision (TV), visual acuity, corneal endothelium and corneal topography investigating possible predictors of efficacy.

Setting:

Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Methods:

30 eyes with progressive keratoconus were enrolled in this prospective study. CXL was performed according to standard Dresden protocol. All patients were corrected with Rose K2 (RK2) contact lenses. Best spectacle–corrected visual acuity (BSCVA), best contact lens-corrected visual acuity (BCLCVA), TV and CS were measured using Vista Vision Far-Pola (DMD MedTech) charts. All patients underwent following diagnostic procedures: autorefractokeratometry (Indo, eRK-10), specular microscopy (Tomey EM-4000) and corneal topography (Pentacam, OCULUS). All parameters were evaluated before CLs fitting, before CXL and 3 and 6 months postoperatively.

Results:

Treated eyes showed a statistically significant improvement of CS, TV and BSCVA. We also found a reduction in keratometry values measured by autorefractokeratometer and corneal topography at 6-months follow-up. Maximum keratometry was significantly lower 6 months postoperatively compared to the preoperative value. Specular microscopy did not show a statistically significant change in endothelial cell parameters at baseline and 6 months postoperatively.

Conclusions:

CXL with riboflavin and UV-A improved visual performance and inhibited the progression of keratoconus. RK2 CLs provided better visual function than spectacles.

Financial Disclosure:

None

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