Posters

Transepithelial corneal cross-linking in treatment of progressive keratoconus

Poster Details

First Author: B.Kambo ALBANIA

Co Author(s):    A. Belshi                    

Abstract Details

Purpose:

The purpose of this study was to evaluate the safety and efficacy of transepithelial corneal collagen cross linking (TE-CXL) with modified riboflavin and accelerated UVA irradiance in thin corneas with pachymetry less than 400 microns at thinnest point.

Setting:

Laser Eye Clinic

Methods:

This study included twenty three eyes of 23 patients with progressive keratoconus who underwent accelerated transepithelial CXL  with 24 months follow up. Modified riboflavin, ParaCel  and vibeX Xtra (riboflavin 0.25%) (Avedro, USA)) were applied to cornea in two stages. Uncorrected and Corrected Distant Visual Acuities (UDVA, CDVA),spherical equivalent (SE), astigmatism, pachymetry at thinnest point (Pachy thin), apex keratometry (Kmax),steep keratometry (steep K) were measured at baseline and at 3, 6,12 and 24 months post operatively. The corneas were irradiated using UVA light for 5 min and 20 s with 45 mW/cm2 irradiance and pulsed illumination

Results:

The mean age of the patient was 22.32 ± 5.24 years. UDVA, CDVA, SE, astigmatism significantly improved at all postoperative test points. Kmax and pachy thin were significantly reduced over baseline at 2 year (p=0.000, 0.004 respectively). Topographic indices did not show significant changes. No intra or post-operative complications were reported.

Conclusions:

Transepithelial accelerated CXL with modified riboflavin is a safe and effective procedure which halt disease progression in thin corneas with progressive keratoconus.

Financial Disclosure:

None