Posters

Collagen cross-linking using photoactivated riboflavin in treatment of resistant infectious keratitis

Poster Details

First Author: H.Duma MACEDONIA

Co Author(s):    V. Reci                    

Abstract Details

Purpose:

To evaluate the efficacy of collagen cross-linking (CXL) using photoactivated riboflavin in treatment of resistant infectious keratitis in antibiotic therapy.

Setting:

University Clinic for Eye Diseases, Skopje, Republic of North Macedonia

Methods:

18 patients with advanced infectious keratitis who did not respond in systemic and topical antibiotic therapy were treated with CXL. The slit-lamp characteristics of the corneal ulceration, corrected distance visual acuity and complication were documented in each patient.

Results:

In 11 patients the infection was stopped following antibiotic therapy after CXL, in 5 patients with corneal melting, the progression of corneal melting was halted after CXL, and in 2 patients with severe form of corneal melting the keratitis did not resolve successfully and in those patients was suggested a penetrating keratoplasty.

Conclusions:

These results indicate that CXL may be an promising option for treating patients with resistant infectious keratitis to prevent further complication as corneal melting and corneal perforation and, the needs for emergency keratoplasty. The success rate was higher for bacterial infections than fungal infections.

Financial Disclosure:

None