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Long-term epithelial remodelling in partial topo-guided ablation combined with CXL (Athens Protocol) for progressive keratoconus (KC)

Poster Details

First Author: M.Chiridou GREECE

Co Author(s):    F. Xhani   A. Kanellopoulos                 

Abstract Details

Purpose:

To evaluate 3D epithelial remodeling over many years following the application of Athens Protocol (AP) for progressive KC

Setting:

LaserVision.gr Clinical and Research Eye Institute, Athens, Greece

Methods:

131 eyes from 94 patients were evaluated over 5 years for UDVA, CDVA, refraction, keratometry, topography and tomograpgy by Scheimpflug and anterior segment OCT that offered the epithelial 3D mapping

Results:

Successful Stabilization and improved refractive data have been reported previously. The overall epithelial thickness over 9mm of central cornea normalized from an average 58 um to 51um (P<0.002) and standard deviation from 2.9n to 1.1 um. Over the thinnest cornea point normalized from 35 um to 51um by month 6, and remained essentially stable over at least 5 years.

Conclusions:

These findings confirm our previous reported work on normalization of overall reactive epithelial thickening in progressive KC with successful CXL here with the AP. Normality of the epithelium over the cone appears to confirm early and long-term biomechanical stability

Financial Disclosure:

None

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