Posters

Predicting outcomes of corneal cross-linking (CXL) for keratoconus

Poster Details

First Author: E.Chan AUSTRALIA

Co Author(s):    H. Yip   S. Sahebjada                 

Abstract Details

Purpose:

To investigate preoperative factors that may influence the outcomes of CXL, and in particular, whether the rate of pre-operative progression affects treatment outcome. The rate of CXL in fellow eyes was also assessed.

Setting:

Royal Victorian Eye and Ear Hospital, Melbourne, Australia

Methods:

This is a retrospective study on patients with progressive keratoconus who underwent CXL at the Royal Victorian Eye and Ear Hospital. All patients who have had CXL who had at least 2 pre-operative visits, and follow-up of at least 11 months after CXL were included in the study. Data collected was collected for each of the 2 visits prior to CXL and the most recent visit after CXL.

Results:

A total of 110 patients were included in the study with a mean age of 21 years. Pre-operatively, there was a moderate to strong correlation between baseline K2 and progression of K2 (r=0.608: patients with higher values of K2 showed greater progression). Sex did not have an effect on K1, K2 or Kmax. Following CXL, K1, K2, Kmax, corneal thickness and cylinder on refraction had no correlation with age, sex or rate of pre-CXL progression. 44 (40%) of eyes had stable keratoconus in the fellow eye during the follow-up period.

Conclusions:

The rate of pre-operative progression does not affect CXL outcomes. Treatment of fellow eyes prior to documentation of progression may also lead to over treatment.

Financial Disclosure:

None