Posters

Predictive factors for visual outcomes of iontophoretic corneal collagen cross-linking for progressive keratoconus

Poster Details

First Author: A.Cantemir ROMANIA

Co Author(s):    A. Alexa   R. Ciuntu   N. Anton   B. Galan   D. Chiselita        

Abstract Details

Purpose:

To evaluate the effect of preoperative predictive factors that might influence the clinical outcomes of iontophoretic corneal collagen crosslinking (I-CXL) in adult patients with progressive keratoconus.

Setting:

Oftaprof Clinic, Iasi, Romania

Methods:

This retrospective study comprised 100 eyes of 100 patients who had  I-CXL for progressive keratoconus. All patients underwent a complete ophthalmological examination and corneal topography at baseline and 1 year. The participants were divided into subgroups with cutoff values according to: age (<30 and >30 years), gender, preoperative CDVA( <0.3 and >0.3 logMAR ), preoperative K max (<54D and >54 D), baseline topographic cone location (central and paracentral), and preoperative thinnest pachymetry (<450microns and >450 microns. Regression analysis was performed to determine the predictive factors for I-CXL outcomes (changes in visual acuity and maximum keratometry).

Results:

In the entire study population, mean CDVA and K max significantly improved after I-CXL (p< 0.001). The only predictive factor for CDVA improvement was low preoperative CDVA (<0.3 logMAR).Predictive factors for K max improvement were low preoperative CDVA (<0.3 logMAR) and thinnest pachymetry less than 450microns.Gender, age, preoperative K max, and baseline topographic cone location did not show significant effect on postoperative visual acuity and maximum keratometry.

Conclusions:

Baseline corrected distance visual acuity and baseline thinnest pachymetry could be predictive factors for the succes of the iontophoretic corneal collagen crosslinking for halting keratoconus progression.

Financial Disclosure:

None